Throwback!See Calista Flockhart, Rob Lowe and the Rest of the ‘Brothers & Sisters’ Cast Then and Now!

Can you believe the first episode of Brothers & Sisters aired nearly 10 years ago? We certainly can't!

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Click through the gallery below to see the hit show's cast — including Rob Lowe, Calista Flockhart and more! — then and now.

Rob Lowe (Robert McCallister)

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